Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913431 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNANPSR1CYP1A2MAPT | |
| SCHEMBL7903245 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNANPSR1CYP1A2MAPT | |
| SCHEMBL7903260 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNANPSR1MAPTALDH1A1 | |
| SCHEMBL11863026 | 0.76 | KMT2A (0.53) | SMN1; SMN2NPSR1CYP2C9CYP1A2MAPT | |
| SCHEMBL7911574 | 0.76 | LMNA (0.43) | SMN1; SMN2LMNANPSR1CYP2C9CYP1A2 | |
| SCHEMBL7910547 | 0.75 | HSD17B10 (0.38) | SMN1; SMN2LMNANPSR1MAPTGAA | |
| SCHEMBL6791972 | 0.74 | ALDH1A1 (0.53) | NPSR1CYP2C9GAAALDH1A1CCNA2 | |
| SCHEMBL7911545 | 0.74 | CCNA2 (0.38) | SMN1; SMN2LMNANPSR1MAPTALDH1A1 | |
| SCHEMBL7916990 | 0.73 | LMNA (0.41) | SMN1; SMN2LMNANPSR1CCNA2CDK2 | |
| SCHEMBL14349873 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNANPSR1HCAR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |