SCHEMBL7912397

SCHEMBL7912397

CC(=O)Oc1ccc2c(C)c(-c3ccccc3)c(=O)oc2c1OC(C)=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 4/20 0.59
ADORA2A P29274 3/20 0.59
ADORA1 P30542 2/20 0.59
KDM4E B2RXH2 8/20 0.59
ALDH1A1 P00352 6/20 0.59
MAPT P10636 4/20 0.59
LMNA P02545 4/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
GAA P10253 3/20 0.59
HPGD P15428 1/20 0.59
MPI P34949 1/20 0.59
POLB P06746 3/20 0.51
HTT P42858 2/20 0.51
RECQL P46063 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
NPC1 O15118 1/20 0.49
STAT1 P42224 1/20 0.49
RAB9A P51151 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8123765 0.91 ADORA3 (0.60) ADORA3ADORA2AADORA1KDM4EALDH1A1
SCHEMBL7941853 0.85 KDM4E (0.69) ADORA3ADORA2AADORA1KDM4EALDH1A1
SCHEMBL9319149 0.82 KDM4E (0.55) ADORA3ADORA2AADORA1KDM4EALDH1A1
SCHEMBL30233473 0.79 MAPT (0.60) ADORA3ADORA2AADORA1KDM4EALDH1A1
SCHEMBL6617327 0.79 MAPT (0.60) ADORA3ADORA2AADORA1KDM4EALDH1A1
SCHEMBL7912467 0.76 KDM4E (0.73) KDM4EALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL27325002 0.75 ADORA3 (0.56) ADORA3ADORA2AADORA1KDM4EALDH1A1
SCHEMBL14301528 0.74 ADORA2A (0.47) ADORA3ADORA2AADORA1KDM4EALDH1A1
SCHEMBL12986404 0.74 KDM4E (0.54) KDM4EALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL12987096 0.74 KDM4E (0.54) KDM4EALDH1A1MAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed