Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MPI | P34949 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912397 | 0.91 | ADORA3 (0.59) | ADORA3ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL7941853 | 0.84 | KDM4E (0.69) | ADORA3ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL6617327 | 0.80 | MAPT (0.60) | ADORA3ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL30233473 | 0.80 | MAPT (0.60) | ADORA3ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL9319149 | 0.75 | KDM4E (0.55) | ADORA3ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL18241777 | 0.73 | ADORA3 (0.49) | ADORA3KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL27459594 | 0.73 | KDM4E (0.55) | ADORA3ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL12941614 | 0.72 | GAA (0.58) | ADORA3ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL3052874 | 0.71 | KDM4E (0.68) | KDM4EMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18241794 | 0.71 | ADORA3 (0.47) | ADORA3ADORA2AADORA1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645382-B1 | COUMARIN DERIVATIVE AND USE THEREOF | MORINAGA MILK INDUSTRY CO LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5574062-A | COMPOUNDS HAVE 3-ARYL AND 7-HYDROXY OR -ACYLOXY; USE TO INHIBIT 12-LIPOXYGENASE | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0645382-A1 | COUMARIN DERIVATIVE AND USE THEREOF | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |