SCHEMBL7912654

SCHEMBL7912654

CC(=O)c1n[nH]c(C(C)=O)c1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
LMNA P02545 2/20 0.52
MAP2 P11137 1/20 0.42
KDM4E B2RXH2 1/20 0.42
RAB9A P51151 1/20 0.41
AKT2 P31751 2/20 0.41
CHEK1 O14757 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
MAPT P10636 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.38
TP53 P04637 1/20 0.38
RET P07949 1/20 0.37
PDGFRB P09619 1/20 0.37
PIM1 P11309 1/20 0.37
PDGFRA P16234 1/20 0.37
GSK3B P49841 1/20 0.37
RPS6KA3 P51812 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20837304 0.81 KMT2A (0.45) ALDH1A1LMNAKDM4EAKT2CHEK1
SCHEMBL10140232 0.72 ADORA3 (0.43) ALDH1A1LMNAKDM4ERAB9ASMN1; SMN2
SCHEMBL13539292 0.72 SMN1; SMN2 (0.50) ALDH1A1LMNAKDM4ERAB9ACHEK1
SCHEMBL27518675 0.70 AKT2 (0.59) ALDH1A1LMNAKDM4ERAB9AAKT2
SCHEMBL6650228 0.70 AKT2 (0.54) LMNAKDM4EAKT2CHEK1KMT2A
SCHEMBL3491623 0.68 RAB9A (0.50) ALDH1A1LMNAKDM4ERAB9AMAPT
SCHEMBL7403288 0.68 LMNA (0.49) ALDH1A1LMNAKDM4EAKT2CHEK1
SCHEMBL15947000 0.67 RAB9A (0.45) ALDH1A1LMNAKDM4ERAB9ACHEK1
SCHEMBL20837285 0.67 LMNA (0.47) ALDH1A1LMNAKDM4EAKT2SMN1; SMN2
SCHEMBL11810834 0.67 SMN1; SMN2 (0.44) ALDH1A1LMNAKDM4ECHEK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed