SCHEMBL7403288

SCHEMBL7403288

O=C(O)c1n[nH]c(O)c1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
KDM4E B2RXH2 2/20 0.49
TP53 P04637 1/20 0.47
PTPN1 P18031 1/20 0.46
HAO2 Q9NYQ3 1/20 0.44
RNASEH1 O60930 1/20 0.42
ERCC1 P07992 1/20 0.42
FEN1 P39748 1/20 0.42
ERCC4 Q92889 1/20 0.42
PIN1 Q13526 2/20 0.42
CYP1A2 P05177 1/20 0.42
MAPK1 P28482 1/20 0.42
CASP1 P29466 1/20 0.42
CYP2C19 P33261 1/20 0.42
HCAR2 Q8TDS4 2/20 0.42
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PRKAB2 O43741 1/20 0.40
PRKAG1 P54619 1/20 0.40
PRKAA2 P54646 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27455057 0.98 LMNA (0.47) LMNAKDM4ETP53PTPN1HAO2
SCHEMBL2222532 0.80 ENPP2 (0.41) LMNAKDM4EHAO2ALDH1A1SMN1; SMN2
SCHEMBL20837285 0.80 LMNA (0.47) LMNAKDM4ETP53PTPN1HAO2
SCHEMBL7402340 0.78 LMNA (0.70) LMNAKDM4ETP53ALDH1A1SMN1; SMN2
SCHEMBL3435970 0.78 LMNA (0.43) LMNAKDM4ETP53PTPN1ERCC1
SCHEMBL15241303 0.75 LMNA (0.42) LMNAKDM4ETP53PTPN1HAO2
SCHEMBL3435968 0.75 PGAM1 (0.39) LMNAKDM4EHAO2PIN1CYP1A2
SCHEMBL15713879 0.75 MEN1 (0.49) LMNAKDM4ETP53CYP1A2MAPK1
SCHEMBL4749775 0.73 AKT2 (0.66) TP53MAPK1MAPTRPS6KA3CHEK1
SCHEMBL11441486 0.73 LMNA (0.41) LMNAKDM4ETP53PTPN1HAO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114867343-A Compositions and methods for controlling plant growth 植物ARC生物技术有限公司 2022-08-05 CN disclosed
CN-110099661-A Whitening dentifrice composition with zinc nucleocapsid silica dioxide granule 高露洁-棕榄公司 2019-08-06 CN disclosed
CN-104519858-B Include the mouthwash of epoxide, the first acid and the second acid 高露洁-棕榄公司 2018-04-20 CN disclosed
CN-104394937-B Liquid activation system 高露洁-棕榄公司 2017-09-22 CN disclosed
CN-103260591-B Metal salt compositions 高露洁-棕榄公司 2016-10-26 CN disclosed
CN-103260466-B Containing hydrophilic active, hydrophobic structure agent and the gelatin encapsulated oral care composition of oil carrier 高露洁-棕榄公司 2016-08-17 CN disclosed
CN-105686328-A HIGH CLEANING DENTIFRICE COMPOSITIONS 高露洁-棕榄公司 2016-06-22 CN disclosed
CN-102764271-B dual component oral care product COLGATE-PALMOLIVE COMPANY (US) 2016-03-02 CN disclosed
CN-103260600-B Aqueous oral care compositions comprising xanthan gum, cellulose gum and carbomer COLGATE-PALMOLIVE CO. (US) 2015-12-02 CN disclosed
CN-105007987-A Oral care compositions and methods of making the same COLGATE PALMOLIVE CO 2015-10-28 CN disclosed
CN-102448425-A Oral care formulations for enhanced soluble zinc levels COLGATE PALMOLIVE CO 2012-05-09 CN disclosed
CN-101938975-A Dual component oral care product COLGATE PALMOLIVE CO 2011-01-05 CN disclosed
CN-1764433-B Hydrogel composition for tooth whitening CORIUM INT 2010-04-28 CN disclosed
CN-101511326-A Method of making a composition comprising a film COLGATE PALMOLIVE CO (US) 2009-08-19 CN disclosed
CN-101018571-A Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components CORIUM INTERNAT INC (US) 2007-08-15 CN disclosed
CN-1933800-A Tooth whitening compositions and methods with reduced peroxide concentration COLGATE PALMOLIVE CO (US) 2007-03-21 CN disclosed
CN-1863519-A Hydrogel compositions with an erodible backing member CORIUM INT (US) 2006-11-15 CN disclosed
CN-1816312-A Hydrogel compositions demonstrating phase separation on contact with aqueous media CORIUM INT (US) 2006-08-09 CN disclosed
CN-1764433-A hydrogel composition for tooth whitening CORIUM INT (US) 2006-04-26 CN disclosed
WO-1997010243-A1 2-(PYRAZOL-5-YL-OXYMETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANOFI (US) 1997-03-20 WO disclosed