Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829326 | 0.90 | MGLL (0.54) | KMT2ABCL9CTNNB1MGLLFAAH | |
| SCHEMBL556964 | 0.87 | KMT2A (0.49) | KMT2AMGLLFAAHTRPV1EPHX2 | |
| SCHEMBL10083799 | 0.84 | KMT2A (0.48) | KMT2ABCL9CTNNB1MGLLFAAH | |
| SCHEMBL14966279 | 0.84 | HTR2A (0.44) | KMT2ABCL9CTNNB1MGLLEPHX2 | |
| SCHEMBL30242885 | 0.84 | KMT2A (0.56) | KMT2ABCL9CTNNB1MGLLFAAH | |
| SCHEMBL14685603 | 0.84 | KMT2A (0.56) | KMT2ABCL9CTNNB1MGLLFAAH | |
| SCHEMBL30678099 | 0.83 | KMT2A (0.45) | KMT2ABCL9CTNNB1MGLLFAAH | |
| SCHEMBL31548905 | 0.83 | KMT2A (0.46) | KMT2AMGLLFAAHTRPV1EPHX2 | |
| SCHEMBL30538270 | 0.81 | MGLL (0.44) | KMT2AMGLLFAAHTRPV1EPHX2 | |
| SCHEMBL30355283 | 0.80 | CASP3 (0.45) | KMT2AMGLLEPHX2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187913-B1 | Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method | GENSET (FR) | 2001-02-13 | — | — | US | disclosed |