Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912741 | 0.90 | KMT2A (0.53) | MGLLKMT2AFAAHTRPV1EPHX2 | |
| SCHEMBL556964 | 0.89 | KMT2A (0.49) | MGLLKMT2AFAAHTRPV1EPHX2 | |
| SCHEMBL14685603 | 0.89 | KMT2A (0.56) | MGLLKMT2AFAAHTRPV1EPHX2 | |
| SCHEMBL30242885 | 0.89 | KMT2A (0.56) | MGLLKMT2AFAAHTRPV1EPHX2 | |
| SCHEMBL30538270 | 0.88 | MGLL (0.44) | MGLLKMT2AFAAHTRPV1EPHX2 | |
| SCHEMBL31548905 | 0.86 | KMT2A (0.46) | MGLLKMT2AFAAHTRPV1EPHX2 | |
| SCHEMBL30355283 | 0.85 | CASP3 (0.45) | MGLLKMT2AEPHX2MAPTHTT | |
| SCHEMBL25357185 | 0.84 | TGM2 (0.51) | MGLLKMT2A | |
| SCHEMBL25357181 | 0.84 | TGM2 (0.51) | MGLLKMT2A | |
| SCHEMBL25357858 | 0.84 | TGM2 (0.51) | MGLLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771440-A4 | GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES | AMGEN INC (US) | 2009-09-02 | — | — | EP | disclosed |
| US-20080070843-A1 | PROTEIN KINASE INHIBITORS COMPRISING ATP MIMETICS CONJUGATED TO PEPTIDES OR PEPTIDOMIMETICS | CUREGENICS LTD. | 2008-03-20 | — | — | US | disclosed |
| EP-1771440-A1 | GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES | Amgen, Inc (US) | 2007-04-11 | — | — | EP | disclosed |
| US-20060089414-A1 | Generic probes for the detection of phosphorylated sequences | AMGEN INC. | 2006-04-27 | — | — | US | disclosed |
| WO-2006014645-A1 | GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES | AMGEN INC. (US) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070843-A1 | PROTEIN KINASE INHIBITORS COMPRISING ATP MIMETICS CONJUGATED TO PEPTIDES OR PEPTIDOMIMETICS | ADK, PRKCQ, IAPP | MGLL 3688/4885KMT2A 2580/4885FAAH 2400/4885 |
| US-20060089414-A1 | Generic probes for the detection of phosphorylated sequences | ACP1, PTPRG, PTPRF | MGLL 3993/4885KMT2A 2775/4885FAAH 4656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.