Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912741 | 0.84 | KMT2A (0.53) | KMT2AMGLLBCL9CTNNB1FAAH | |
| SCHEMBL3829326 | 0.80 | MGLL (0.54) | KMT2AMGLLBCL9CTNNB1FAAH | |
| SCHEMBL25357185 | 0.78 | TGM2 (0.51) | KMT2AMGLLTLR2 | |
| SCHEMBL25357858 | 0.78 | TGM2 (0.51) | KMT2AMGLLTLR2 | |
| SCHEMBL25357181 | 0.78 | TGM2 (0.51) | KMT2AMGLLTLR2 | |
| SCHEMBL25358031 | 0.78 | KMT2A (0.51) | KMT2AMGLLTLR2 | |
| SCHEMBL25358036 | 0.78 | KMT2A (0.51) | KMT2AMGLLTLR2 | |
| SCHEMBL556964 | 0.76 | KMT2A (0.49) | KMT2AMGLLFAAHTRPV1MAPT | |
| SCHEMBL4956399 | 0.76 | KMT2A (0.45) | KMT2AMGLLFAAHTRPV1TLR2 | |
| SCHEMBL29989659 | 0.75 | TGM2 (0.46) | KMT2AMGLLFAAHTRPV1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016128-A1 | Rhodamine lactone phosphoramidites and polymers | AAT BIOQUEST, INC. | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016128-A1 | Rhodamine lactone phosphoramidites and polymers | PHYKPL, PFAS, PHOSPHO1 | KMT2A 3210/4885MGLL 1062/4885BCL9 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.