Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913218 | 0.96 | ACHE (0.42) | ACHEOPRK1KDM4EKMT2ANPC1 | |
| SCHEMBL7911353 | 0.87 | KDM4E (0.52) | ACHEOPRK1KDM4EKMT2ANPC1 | |
| SCHEMBL7911302 | 0.86 | ACHE (0.46) | ACHEOPRK1KDM4EKMT2ANPC1 | |
| SCHEMBL927361 | 0.84 | ACHE (0.41) | ACHEOPRK1KDM4EKMT2ANPC1 | |
| SCHEMBL7913313 | 0.83 | KDM4E (0.50) | ACHEOPRK1KDM4EKMT2ANPC1 | |
| SCHEMBL14884990 | 0.83 | NPSR1 (0.36) | ACHEOPRK1KDM4EKMT2ANPC1 | |
| SCHEMBL927301 | 0.83 | ACHE (0.41) | ACHEOPRK1KDM4EKMT2ANPC1 | |
| SCHEMBL7903015 | 0.82 | ACHE (0.44) | ACHEOPRK1KDM4EKMT2ANPC1 | |
| SCHEMBL927383 | 0.80 | OPRK1 (0.39) | ACHEOPRK1KDM4EKMT2ANPC1 | |
| SCHEMBL7903007 | 0.79 | SLC9A1 (0.39) | KDM4EALDH1A1RAB9ASLC9A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |