Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902818 | 0.84 | SLC6A3 (0.35) | SLC6A3CHRM3LMNAMAPTMEN1 | |
| SCHEMBL7911681 | 0.83 | MAPT (0.36) | SLC6A3CHRM3LMNAMAPTMEN1 | |
| SCHEMBL7911686 | 0.82 | PGR (0.34) | LMNAMAPTMEN1ALDH1A1ALOX12 | |
| SCHEMBL7914051 | 0.82 | SLC6A3 (0.35) | SLC6A3CHRM3LMNAMAPTMEN1 | |
| SCHEMBL7910125 | 0.80 | PGR (0.34) | MAPTMEN1ALDH1A1KMT2APGR | |
| SCHEMBL7912990 | 0.78 | PARP1 (0.37) | SLC6A3LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL7921942 | 0.76 | CHRM3 (0.31) | CHRM3LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL7929296 | 0.75 | DYRK3 (0.49) | CHRM3LMNAMAPTALDH1A1JAK2 | |
| SCHEMBL7902852 | 0.75 | NPC1 (0.34) | MAPTKMT2ADYRK3DYRK1ADYRK2 | |
| SCHEMBL7913253 | 0.75 | MAOB (0.34) | LMNAMAPTALDH1A1ALOX12PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010059836-A1 | SUBSTITUTED AZA-BRIDGED BICYCLICS FOR CARDIOVASCULAR AND CNS DISEASE | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |