Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787888 | 0.85 | ACHE (0.52) | ACHESIGMAR1ALDH1A1MAPK1PARP1 | |
| SCHEMBL29611864 | 0.83 | ACHE (0.50) | ACHESIGMAR1ALDH1A1MAPK1PARP1 | |
| SCHEMBL6303647 | 0.83 | ACHE (0.50) | ACHESIGMAR1ALDH1A1MAPK1PARP1 | |
| SCHEMBL27854433 | 0.81 | ACHE (0.48) | ACHESIGMAR1ALDH1A1MAPK1PARP1 | |
| SCHEMBL11680537 | 0.81 | ACHE (0.48) | ACHESIGMAR1ALDH1A1MAPK1PARP1 | |
| SCHEMBL22567133 | 0.79 | ACHE (0.46) | ACHESIGMAR1ALDH1A1TAAR1IDO1 | |
| SCHEMBL28895569 | 0.79 | SIGMAR1 (0.46) | ACHESIGMAR1ALDH1A1MAPK1HTR3E | |
| SCHEMBL31298550 | 0.79 | ACHE (0.46) | ACHESIGMAR1ALDH1A1TAAR1IDO1 | |
| SCHEMBL977663 | 0.79 | ACHE (0.58) | ACHESIGMAR1ALDH1A1MAPK1HSD17B1 | |
| SCHEMBL12879 | 0.77 | ALDH1A1 (0.56) | ACHESIGMAR1ALDH1A1MAPK1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1205179-C | (P-aminohydroxyphenyl) acrylamide derivatives and coloring agents containing the same | P & G CLAROLL CORP (US) | 2005-06-08 | — | — | CN | claimed |
| CN-1437578-A | (P-amino-hyaroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2003-08-20 | — | — | CN | claimed |
| US-6228816-B1 | AQUEOUS CUTTING LIQUID WHICH COMPRISES CATIONIC WATER-SOLUBLE RESIN HAVING SPECIFIED AMINE VALUE AND AT LEAST ONE RHEOLOGY CONTROL AGENT SELECTED FROM INORGANIC BENTONITE, ORGANIC BENTONITE AND AQUEOUS SILICA SOL | NOF CORPORATION (JP) | 2001-05-08 | — | — | US | disclosed |