Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911568 | 0.87 | MAOB (0.52) | ITGB3ITGA2BCYP24A1CYP26A1FAAH | |
| SCHEMBL9621126 | 0.81 | THRA (0.54) | ITGB3ITGA2BCYP24A1CYP19A1CYP26A1 | |
| SCHEMBL19128297 | 0.72 | CYP24A1 (0.51) | CYP24A1CYP19A1CYP26A1CYP27A1 | |
| SCHEMBL7911591 | 0.71 | MAOA (0.70) | MAOAMAOB | |
| SCHEMBL1814998 | 0.71 | ACHE (0.38) | CYP24A1CYP19A1CYP26A1CYP27A1 | |
| SCHEMBL5665208 | 0.70 | MAOB (0.52) | ITGB3ITGA2BCYP24A1CYP26A1FAAH | |
| SCHEMBL17261698 | 0.70 | TRPV1 (0.41) | CYP24A1CYP19A1CYP26A1CYP27A1 | |
| SCHEMBL20572886 | 0.69 | MAOB (0.54) | ITGB3ITGA2BCYP24A1CYP26A1MAOA | |
| SCHEMBL8192077 | 0.69 | ACACB (0.48) | ITGB3ITGA2BMAOAMAOB | |
| SCHEMBL8192080 | 0.69 | ACACB (0.48) | ITGB3ITGA2BMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |