Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430185 | 0.83 | NPC1 (0.44) | RAB9ANPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL14257518 | 0.82 | RAB9A (0.66) | RAB9ANPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL5163597 | 0.81 | MAPT (0.44) | NPC1KDM4ESMN1; SMN2HSD17B10CYP2C19 | |
| SCHEMBL5550293 | 0.80 | GAA (0.42) | KDM4ESMN1; SMN2HSD17B10CYP2C19MAPT | |
| SCHEMBL13539892 | 0.79 | RAB9A (0.62) | RAB9ANPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL28131880 | 0.78 | ACACB (0.61) | RAB9ANPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL5546836 | 0.78 | TP53 (0.37) | RAB9ANPC1MAPTALDH1A1GAA | |
| SCHEMBL17212283 | 0.78 | NPC1 (0.40) | RAB9ANPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7100996 | 0.77 | NPC1 (0.46) | RAB9ANPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7097844 | 0.77 | LTA4H (0.44) | RAB9ANPC1KDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6217856-B1 | SUNSCREEN AGENTS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-04-17 | — | — | US | disclosed |