SCHEMBL4430185

SCHEMBL4430185

CCCCC(CC)COc1ccc(-c2nc(-c3ccc(OCC(CC)CCCC)cc3)nc(-c3ccc(OCC(CC)CCCC)cc3)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
KDM4E B2RXH2 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP2C19 P33261 3/20 0.42
CYP19A1 P11511 2/20 0.42
CYP2C9 P11712 2/20 0.42
ALDH1A1 P00352 6/20 0.42
MAPT P10636 3/20 0.42
HPGD P15428 2/20 0.42
CYP1A2 P05177 2/20 0.42
GAA P10253 1/20 0.42
CYP3A4 P08684 5/20 0.41
CYP2D6 P10635 2/20 0.41
CA2 P00918 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17212283 0.94 NPC1 (0.40) NPC1RAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL7100996 0.93 NPC1 (0.46) NPC1RAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL7098517 0.93 ALDH1A1 (0.40) NPC1RAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL7097844 0.93 LTA4H (0.44) NPC1RAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL20357876 0.89 CYP3A4 (0.47) HSD17B10CYP2C19CYP19A1CYP2C9ALDH1A1
SCHEMBL17831410 0.88 LMNA (0.39) NPC1RAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL7097913 0.88 LMNA (0.39) NPC1RAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL1356320 0.87 ALDH1A1 (0.50) HSD17B10ALDH1A1CYP3A4CA2L3MBTL1
SCHEMBL1357035 0.87 ALDH1A1 (0.50) HSD17B10ALDH1A1CYP3A4CA2L3MBTL1
SCHEMBL23784451 0.86 LMNA (0.37) NPC1RAB9AKDM4ESMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1768644-B1 LIGHT PROTECTING-EFFECTIVE COSMETIC OR DERMATOLOGICAL PREPARATIONS CIBA HOLDING INC (CH) 2009-02-18 EP claimed
CN-112074736-B UV filter composition, method for the production thereof and use thereof 巴斯夫欧洲公司 2024-10-01 CN disclosed
CN-116782923-A Scar treatment composition 塔普克斯制药公司 2023-09-19 CN disclosed
CN-116710081-A Scar treatment composition 塔普克斯制药公司 2023-09-05 CN disclosed
CN-116075310-A Topical vitamin C compositions 塔普克斯制药公司 2023-05-05 CN disclosed
US-6217856-B1 SUNSCREEN AGENTS CIBA SPECIALTY CHEMICALS CORPORATION 2001-04-17 US disclosed
EP-0941217-A1 SYMMETRICAL TRIAZINE DERIVATIVES Ciba SC Holding AG (CH) 1999-09-15 EP disclosed
WO-1998022447-A1 SYMMETRICAL TRIAZINE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-05-28 WO disclosed