Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910318 | 0.89 | MAPT (0.43) | MAPTHTTSMN1; SMN2RAB9AATM | |
| SCHEMBL7902756 | 0.80 | CYP19A1 (0.47) | MAPTHTTSMN1; SMN2RAB9AATM | |
| SCHEMBL7902758 | 0.80 | CYP19A1 (0.47) | MAPTHTTSMN1; SMN2RAB9AATM | |
| SCHEMBL7902752 | 0.80 | CYP19A1 (0.47) | MAPTHTTSMN1; SMN2RAB9AATM | |
| SCHEMBL7913231 | 0.75 | SLC9A1 (0.41) | MAPTHTTSMN1; SMN2RAB9AATM | |
| SCHEMBL7903042 | 0.73 | SLC9A1 (0.39) | MAPTHTTSMN1; SMN2RAB9AATM | |
| SCHEMBL7916790 | 0.72 | CHRNB2 (0.35) | LMNAALDH1A1 | |
| SCHEMBL7912931 | 0.72 | SLC9A1 (0.59) | MAPTHTTSMN1; SMN2RAB9AATM | |
| SCHEMBL7912979 | 0.71 | EEF2K (0.39) | HTTRAB9ACYP11B1CYP11B2LMNA | |
| SCHEMBL927184 | 0.71 | SLC9A1 (0.61) | MAPTHTTSMN1; SMN2RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |