Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | PDE5A | O76074 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | PDE1A | P54750 | 1/20 | 0.59 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.59 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | FADS1 | O60427 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912186 | 0.89 | MAPT (0.55) | KDRMAPTALDH1A1HPGDCA1 | |
| SCHEMBL7915131 | 0.85 | SHMT2 (0.46) | KDRMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7913375 | 0.84 | KDR (0.62) | KDRMAPTCA1CA2ABCG2 | |
| SCHEMBL7918387 | 0.84 | MAPT (0.75) | KDRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7918376 | 0.82 | KDR (0.44) | KDRMAPTCA1CA2EGFR | |
| SCHEMBL7914911 | 0.81 | MEN1 (0.52) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7913393 | 0.81 | EGFR (0.47) | KDRMAPTEGFRLMNAMEN1 | |
| SCHEMBL1752920 | 0.75 | MAPT (1.00) | KDRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29478480 | 0.75 | MAPT (1.00) | KDRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29478484 | 0.75 | MAPT (1.00) | KDRMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |