Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913393 | 0.92 | EGFR (0.47) | KDREGFRMAPTLMNAPDGFRB | |
| SCHEMBL7912186 | 0.88 | MAPT (0.55) | KDREGFRMAPTLMNACA9 | |
| SCHEMBL7914832 | 0.83 | MAPT (0.61) | KDRMAPTLMNAMEN1KMT2A | |
| SCHEMBL7918683 | 0.82 | KDR (0.60) | KDREGFRMAPTLMNAPDGFRB | |
| SCHEMBL7912095 | 0.77 | MAPT (0.62) | KDREGFRMAPTLMNAMEN1 | |
| SCHEMBL7915131 | 0.76 | SHMT2 (0.46) | KDRMAPTLMNASHMT2MEN1 | |
| SCHEMBL7913375 | 0.75 | KDR (0.62) | KDREGFRMAPTLMNAPDGFRB | |
| SCHEMBL7914911 | 0.75 | MEN1 (0.52) | MAPTLMNASHMT2MEN1KMT2A | |
| SCHEMBL7904933 | 0.75 | MAPT (0.63) | KDRMAPTLMNACA9ENPP3 | |
| SCHEMBL7914879 | 0.74 | EGFR (0.53) | KDREGFRMAPTLMNACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |