Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584737 | 0.75 | BRD4 (0.34) | PARP1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL2461954 | 0.73 | BRD4 (0.47) | KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL2464368 | 0.71 | BRD4 (0.44) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL7910808 | 0.69 | KDM4E (0.34) | PARP1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL2587071 | 0.64 | KDM4E (0.37) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL2465486 | 0.64 | KDM4E (0.38) | PARP1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL2462305 | 0.62 | KDM4E (0.39) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL9621241 | 0.57 | HSD17B1 (0.45) | NPSR1 | |
| SCHEMBL2461981 | 0.55 | HTR2A (0.42) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL2463055 | 0.55 | MAPT (0.50) | KDM4EALDH1A1TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064735-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |