SCHEMBL2587071

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2462305	0.98	KDM4E (0.39)	KDM4EIDO1MAPTBRD4HRH3
	SCHEMBL2582111	0.85	HRH3 (0.35)	KDM4EIDO1HRH3ALDH1A1HSD17B10
	SCHEMBL2581768	0.85	ALDH1A1 (0.35)	KDM4EIDO1MAPTHRH3ALDH1A1
	SCHEMBL2575816	0.83	KDM4E (0.36)	KDM4EMAPTALDH1A1HSD17B10TSHR
	SCHEMBL12160476	0.83	HRH3 (0.36)	KDM4EIDO1HRH3ALDH1A1HSD17B10
	SCHEMBL2459170	0.83	MAOA (0.35)	KDM4EIDO1MAPTHRH3ALDH1A1
	SCHEMBL2465486	0.82	KDM4E (0.38)	KDM4EMAPTALDH1A1HSD17B10TSHR
	SCHEMBL2461954	0.82	BRD4 (0.47)	KDM4EMAPTBRD4ALDH1A1HPGD
	SCHEMBL2461744	0.81	PDE2A (0.35)	KDM4EIDO1HRH3ALDH1A1HSD17B10
	SCHEMBL2581572	0.80	KDM4E (0.37)	KDM4EMAPTALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.