Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725156 | 0.97 | HSD11B1 (0.47) | DHODHCTSVCTSLHSD11B1BCHE | |
| SCHEMBL7909535 | 0.92 | CTSV (0.51) | DHODHCTSVCTSLHSD11B1RARB | |
| SCHEMBL3728181 | 0.90 | CTSV (0.49) | CTSVCTSLHSD11B1RARBTP53 | |
| SCHEMBL3724388 | 0.90 | CTSV (0.49) | CTSVCTSLHSD11B1RARBTP53 | |
| SCHEMBL596598 | 0.85 | SIGMAR1 (0.44) | DHODHCTSVCTSLHSD11B1BCHE | |
| SCHEMBL6059665 | 0.84 | CTSV (0.49) | DHODHCTSVCTSLHSD11B1RARB | |
| SCHEMBL6830669 | 0.83 | CTSV (0.45) | DHODHCTSVCTSLHSD11B1CNR2 | |
| SCHEMBL3725185 | 0.83 | HSD11B1 (0.50) | DHODHCTSVCTSLHSD11B1RARB | |
| SCHEMBL27942363 | 0.81 | ESR1 (0.44) | HSD11B1TSHRPSMB5ESR1ESR2 | |
| SCHEMBL13650127 | 0.81 | CASP3 (0.44) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6203933-B1 | ELECTROLUMINESCENT ELEMENT WITH LIGHT EMITTER LAYER AND HOLE INJECTING AND TRANSPORTATING COMPOUND | TDK CORPORATION (JP) | 2001-03-20 | — | — | US | disclosed |