SCHEMBL7913749

SCHEMBL7913749

CCOCC1CCC(C2CCC(c3ccc(C(F)(F)C(F)C(F)(F)F)cc3)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.32
ACACB O00763 4/20 0.32
IDO1 P14902 1/20 0.32
HTR2C P28335 2/20 0.31
MEN1 O00255 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
ESR2 Q92731 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
GPR119 Q8TDV5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913629 0.93 ALDH1A1 (0.33) ALDH1A1LMNAMAPTCYP2C9ACACB
SCHEMBL7914093 0.88 HTR2C (0.33) ALDH1A1LMNAMAPTCYP2C9ACACB
SCHEMBL7911200 0.86 ALDH1A1 (0.38) ALDH1A1LMNAMAPTCYP2C9ACACB
SCHEMBL7911161 0.85 IDO1 (0.31) IDO1HTR2CGPR119
SCHEMBL7914131 0.81 ALDH1A1 (0.50) ALDH1A1LMNAMAPTCYP2C9IDO1
SCHEMBL7913858 0.81 DGAT1 (0.34) ALDH1A1LMNAMAPTCYP2C9ACACB
SCHEMBL7917585 0.80 ALDH1A1 (0.49) ALDH1A1LMNAMAPTCYP2C9IDO1
SCHEMBL7911198 0.79 ALDH1A1 (0.38) ALDH1A1LMNAMAPTCYP2C9ACACB
SCHEMBL7911955 0.79 SLC6A2 (0.30) SLC6A2SLC6A4SLC6A3
SCHEMBL7903467 0.79 HTR2C (0.31) IDO1HTR2CGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed