Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593409 | 0.87 | PDE5A (0.63) | PDE5A | |
| SCHEMBL7914747 | 0.85 | PDE5A (0.55) | PDE5A | |
| SCHEMBL8620057 | 0.77 | PDE5A (0.71) | PDE5A | |
| SCHEMBL7904428 | 0.75 | PDE5A (0.54) | PDE5APDE2A | |
| SCHEMBL6594486 | 0.74 | PDE5A (0.63) | PDE5APDE2A | |
| SCHEMBL5598718 | 0.73 | PDE4A (0.57) | PDE5APDE2A | |
| SCHEMBL6592174 | 0.72 | PDE5A (0.58) | PDE5APDE2A | |
| SCHEMBL7914746 | 0.71 | PDE4A (0.53) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6598895 | 0.70 | PDE5A (1.00) | PDE5APDE2A | |
| SCHEMBL27504950 | 0.70 | PDE5A (0.85) | PDE5APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218392-B1 | FOR THERAPY AND PROPHYLAXIS OF ISCHEMIC HEART DISEASES SUCH AS ANGINA PECTORIS, MYOCARDIAL INFARCT AND CHRONIC AND ACUTE CARDIAC FAILURE, PULMONARY HYPERTENSION, ARTERIOSCLEROSIS AND BRONCHIAL ASTHMA | EISAI CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| US-5849741-A | Fused pyridazine compounds | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |