Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.62 |
| ▸ | CCR6 | P51684 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702171 | 0.77 | HKDC1 (1.00) | MEN1KMT2AHKDC1PABPC1CCR6 | |
| SCHEMBL16296885 | 0.74 | HSP90AA1 (1.00) | MEN1KMT2AHKDC1PABPC1CCR6 | |
| SCHEMBL27509970 | 0.72 | MEN1 (0.46) | MEN1KMT2AHKDC1PABPC1CCR6 | |
| SCHEMBL16297016 | 0.72 | HSP90AA1 (0.67) | MEN1KMT2AHKDC1PABPC1CCR6 | |
| SCHEMBL7956944 | 0.72 | HSP90AA1 (1.00) | MEN1KMT2AHKDC1PABPC1CCR6 | |
| SCHEMBL22085391 | 0.71 | KMT2A (0.59) | MEN1KMT2AHDAC6HDAC3CA12 | |
| SCHEMBL27622875 | 0.71 | HDAC1 (0.65) | MEN1KMT2AHDAC6HDAC3CA12 | |
| SCHEMBL1965784 | 0.71 | MEN1 (0.80) | MEN1KMT2AHDAC6HDAC2HDAC8 | |
| SCHEMBL11847585 | 0.70 | MEN1 (0.58) | MEN1KMT2AHKDC1PABPC1CCR6 | |
| SCHEMBL24202631 | 0.70 | SIRT1 (0.83) | MEN1KMT2AHDAC6HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214990-B1 | 2,9-BIS(4-METHOXYBENZOYLOXY),3,10-DIMETHOXY,6,13-DICHLORO -PHENODIOXAZINE, FOR EXAMPLE; DYE HAS NARROW LIGHT ABORPTION BAND AND HIGH DICHROIC RATIO | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |