SCHEMBL7915048

SCHEMBL7915048

Nc1ccc2c(c1)-c1cc(N)ccc1C(=O)C2=O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 3/20 0.82
NPC1 O15118 6/20 0.74
RAB9A P51151 6/20 0.74
ALDH1A1 P00352 4/20 0.74
SMN1; SMN2 Q16637 4/20 0.74
LMNA P02545 4/20 0.74
MEN1 O00255 4/20 0.74
KMT2A Q03164 4/20 0.74
NPSR1 Q6W5P4 4/20 0.74
APAF1 O14727 3/20 0.74
HTT P42858 3/20 0.74
GALK1 P51570 3/20 0.74
BLM P54132 3/20 0.74
POLB P06746 3/20 0.74
PTBP1 P26599 2/20 0.74
SMAD3 P84022 2/20 0.74
TDP2 O95551 2/20 0.74
PLA2G1B P04054 2/20 0.74
PLCG1 P19174 2/20 0.74
S100A4 P26447 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9019051 0.94 NPC1 (0.77) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL6262683 0.91 PTPRC (1.00) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL31087632 0.90 NPC1 (0.78) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL9019017 0.90 NPC1 (0.78) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL3135129 0.89 NPC1 (0.86) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL5551699 0.89 S100A4 (0.82) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL28005394 0.86 NPC1 (0.82) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL30043508 0.85 PTPRC (1.00) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL30350052 0.83 NPC1 (0.77) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL864582 0.83 NPC1 (0.77) PTPRCNPC1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0482593-B1 Polymer scale preventive agent, polymerization vessel for preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1995-01-11 EP claimed
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0482593-B1 Polymer scale preventive agent, polymerization vessel for preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1995-01-11 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed