Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267132 | 0.84 | SLC6A3 (0.51) | ALDH1A1HSD17B10CFTRSLC6A3SLC6A4 | |
| SCHEMBL14812308 | 0.84 | GAA (0.54) | GAAALDH1A1HSD17B10CFTRSLC6A3 | |
| SCHEMBL22256464 | 0.83 | MAPT (0.47) | ALDH1A1HSD17B10CFTRSLC6A3SLC6A4 | |
| SCHEMBL7570354 | 0.83 | KDM4E (0.53) | GAAALDH1A1HSD17B10SLC6A3SLC6A4 | |
| SCHEMBL628630 | 0.82 | LOXL2 (0.50) | GAAALDH1A1HSD17B10CFTRSLC6A3 | |
| SCHEMBL9549 | 0.82 | SLC6A3 (0.57) | ALDH1A1HSD17B10CFTRSLC6A3SLC6A4 | |
| SCHEMBL628811 | 0.82 | SLC6A3 (0.46) | ALDH1A1HSD17B10CFTRSLC6A3SLC6A4 | |
| SCHEMBL6775709 | 0.82 | ALDH1A1 (0.51) | GAAALDH1A1HSD17B10CFTRSLC6A3 | |
| SCHEMBL29775249 | 0.81 | GAA (0.58) | GAAALDH1A1HSD17B10CFTRSLC6A3 | |
| SCHEMBL630047 | 0.81 | GAA (0.58) | GAAALDH1A1HSD17B10CFTRSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |
| WO-1998050030-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |