Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918595 | 0.88 | FNTA (0.40) | LTB4R2 | |
| SCHEMBL7917806 | 0.88 | CNR1 (0.41) | ESR1ESR2LTB4R2CNR1CNR2 | |
| SCHEMBL7918697 | 0.78 | BRS3 (0.37) | MYCMCL1PPARG | |
| SCHEMBL7921829 | 0.77 | FNTA (0.39) | CNR1CNR2 | |
| SCHEMBL7918518 | 0.74 | MYC (0.39) | MYCMCL1BADPPARGPPARA | |
| SCHEMBL7916606 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL29064695 | 0.69 | MYC (0.56) | MYCMCL1 | |
| SCHEMBL9139879 | 0.68 | MCL1 (0.55) | MYCMCL1ESR1ESR2 | |
| SCHEMBL629880 | 0.68 | MYC (0.54) | MYCMCL1 | |
| SCHEMBL629058 | 0.67 | MYC (0.50) | MYCMCL1LTB4R2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |