Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916885 | 0.86 | PTGS1 (0.35) | LMNAPTGS1PDE4ASLC6A6CYP2C19 | |
| SCHEMBL6887308 | 0.75 | INPP5A (0.35) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL28158346 | 0.73 | CXCR4 (0.34) | — | |
| SCHEMBL3623041 | 0.70 | — | — | |
| SCHEMBL353883 | 0.69 | KMT2A (0.54) | LMNACYP2C19CYP3A4TSHR | |
| SCHEMBL2169002 | 0.68 | GABRA5 (0.46) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL8078390 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL29891111 | 0.67 | GABRA5 (0.45) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL21063501 | 0.67 | LMNA (0.35) | LMNAPTGS1PDE4ASLC6A6CYP2C19 | |
| SCHEMBL10511006 | 0.67 | LMNA (0.35) | LMNAPTGS1PDE4ASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074921-A1 | SULFONATE-CONTAINING POLYURETHANE DISPERSIONS VIA NON-SOLVENT PROCESS | CROMPTON CORPORATION (US) | 2001-10-11 | — | — | WO | disclosed |