Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921419 | 0.91 | LMNA (0.50) | LMNATSHRTP53ALDH1A1HTT | |
| SCHEMBL7921747 | 0.85 | LMNA (0.62) | LMNATSHRTP53ALDH1A1HTT | |
| SCHEMBL7921838 | 0.83 | LMNA (0.60) | LMNATSHRTP53ALDH1A1HTT | |
| SCHEMBL7924027 | 0.83 | LMNA (0.48) | LMNATSHRTP53ALDH1A1HTT | |
| SCHEMBL7915455 | 0.82 | LMNA (0.58) | LMNATSHRTP53ALDH1A1HTT | |
| SCHEMBL7921984 | 0.81 | ALDH1A1 (0.57) | LMNATSHRTP53ALDH1A1HTT | |
| SCHEMBL7924163 | 0.81 | LMNA (0.47) | LMNATSHRTP53ALDH1A1HTT | |
| SCHEMBL7921621 | 0.81 | ALDH1A1 (0.76) | LMNATSHRTP53ALDH1A1HTT | |
| SCHEMBL7921619 | 0.80 | LMNA (0.49) | LMNATSHRTP53ALDH1A1HTT | |
| SCHEMBL7915290 | 0.80 | KDM4E (0.58) | LMNATSHRALDH1A1HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |