Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921621 | 0.91 | ALDH1A1 (0.76) | LMNATSHRALDH1A1HPGDALOX15 | |
| SCHEMBL7921771 | 0.90 | LMNA (0.61) | LMNATSHRALDH1A1HPGDALOX15 | |
| SCHEMBL7594639 | 0.90 | LMNA (0.61) | LMNATSHRALDH1A1HPGDALOX15 | |
| SCHEMBL7921838 | 0.89 | LMNA (0.60) | LMNATSHRALDH1A1HPGDALOX15 | |
| SCHEMBL7921776 | 0.88 | LMNA (0.58) | LMNATSHRALDH1A1HTTTP53 | |
| SCHEMBL7927377 | 0.86 | LMNA (0.56) | LMNATSHRALDH1A1TP53MAPT | |
| SCHEMBL7921419 | 0.85 | LMNA (0.50) | LMNATSHRALDH1A1HPGDALOX15 | |
| SCHEMBL7915283 | 0.85 | LMNA (0.50) | LMNATSHRALDH1A1HPGDALOX15 | |
| SCHEMBL7921975 | 0.84 | ALDH1A1 (0.60) | LMNATSHRALDH1A1ALOX15TP53 | |
| SCHEMBL7924133 | 0.84 | LMNA (0.48) | LMNATSHRALDH1A1ALOX15PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |