Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | DRD4 | P21917 | 3/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | HRH2 | P25021 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MPI | P34949 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924162 | 0.90 | KDM4E (0.62) | KDM4ELMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL7915455 | 0.88 | LMNA (0.58) | KDM4ELMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL7921984 | 0.87 | ALDH1A1 (0.57) | KDM4ELMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL7921621 | 0.84 | ALDH1A1 (0.76) | KDM4ELMNAHTTMAPTALOX15 | |
| SCHEMBL7927375 | 0.84 | KDM4E (0.54) | KDM4ELMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL7927315 | 0.83 | KDM4E (0.58) | KDM4ELMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL7923134 | 0.83 | KDM4E (0.53) | KDM4ELMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL7921648 | 0.83 | DRD4 (0.54) | KDM4ELMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL7924163 | 0.82 | LMNA (0.47) | KDM4ELMNAHTTMAPTTDP1 | |
| SCHEMBL7921776 | 0.82 | LMNA (0.58) | KDM4ELMNAHTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |