Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927267 | 0.88 | MAPT (0.49) | LMNAALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL7921747 | 0.88 | LMNA (0.62) | LMNAALDH1A1TSHRMAPTHTT | |
| SCHEMBL7921621 | 0.88 | ALDH1A1 (0.76) | LMNAALDH1A1TSHRMAPTHTT | |
| SCHEMBL7921771 | 0.87 | LMNA (0.61) | LMNAALDH1A1TSHRMAPTGAA | |
| SCHEMBL7594639 | 0.87 | LMNA (0.61) | LMNAALDH1A1TSHRMAPTGAA | |
| SCHEMBL7924163 | 0.85 | LMNA (0.47) | LMNAALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL7927377 | 0.83 | LMNA (0.56) | LMNAALDH1A1TSHRMAPTGAA | |
| SCHEMBL7927355 | 0.83 | DRD2 (0.46) | LMNAALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL7921790 | 0.83 | DRD2 (0.46) | LMNAALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL7915290 | 0.82 | KDM4E (0.58) | LMNAALDH1A1TSHRMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |