Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15436237 | 0.82 | PIM1 (0.45) | MBOAT4HTTRECQLKDM4EGLA | |
| Hydrochloric Acid SCHEMBL15436253 | 0.81 | PIM1 (0.44) | MBOAT4HTTRECQLKDM4EGLA | |
| Hydrochloric Acid SCHEMBL27850418 | 0.81 | PIM1 (0.44) | MBOAT4HTTRECQLKDM4EGLA | |
| SCHEMBL7910798 | 0.77 | KDM4E (0.46) | HTTKDM4EHSP90AA1ALDH1A1CYP1A2 | |
| SCHEMBL3389640 | 0.76 | WNT3A (0.35) | MBOAT4HTTRECQLMEN1KMT2A | |
| SCHEMBL2470786 | 0.74 | PIM2 (0.40) | KDM4EMEN1KMT2AALDH1A1PIM1 | |
| SCHEMBL31372672 | 0.74 | PIM2 (0.40) | KDM4EMEN1KMT2AALDH1A1PIM1 | |
| SCHEMBL7911485 | 0.74 | CDK2 (0.41) | HTTKDM4EGLAALDH1A1ROCK1 | |
| SCHEMBL19376940 | 0.73 | ALOX5AP (0.44) | MBOAT4ALOX5APFEN1PIK3CDPIK3CA | |
| SCHEMBL15436242 | 0.73 | DHFR (0.46) | MBOAT4HTTRECQLKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063663-A1 | N-{[(IR,4S,6R-3-(2-PYRIDINYLCARBONYL)-3-AZABICYCLO [4.1.0]HEPT-4-YL] METHYL}-2-HETEROARYLAMINE DERIVATIVES AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2010-06-10 | — | — | WO | disclosed |