Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.61 |
| ▸ | DRD1 | P21728 | 3/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15340829 | 0.85 | NPSR1 (0.49) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL10365263 | 0.80 | ALDH1A1 (0.55) | OPRM1CHRM2ADRA2ADRD3KCNH2 | |
| SCHEMBL27356097 | 0.80 | OPRM1 (0.53) | OPRM1CYP2D6OPRD1OPRK1OPRL1 | |
| SCHEMBL10674933 | 0.80 | CACNA2D1 (0.55) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL9257372 | 0.80 | OPRM1 (0.54) | OPRM1CYP2D6OPRD1OPRK1OPRL1 | |
| SCHEMBL8122955 | 0.80 | OPRD1 (0.65) | OPRM1CYP2D6OPRD1OPRK1OPRL1 | |
| SCHEMBL2056220 | 0.80 | MEN1 (0.56) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL8305212 | 0.80 | CACNA2D1 (0.54) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL27015356 | 0.79 | OPRM1 (0.68) | OPRM1CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL9439094 | 0.78 | OPRM1 (0.53) | OPRM1CHRM2ADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |