Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.54 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915438 | 0.80 | OPRM1 (0.61) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL3263616 | 0.79 | CHRM2 (0.60) | CACNA2D1CACNB1CACNA1BCACNA1COPRD1 | |
| SCHEMBL3261754 | 0.78 | ACHE (0.54) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL3263286 | 0.78 | CHRM2 (0.58) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL27356097 | 0.75 | OPRM1 (0.53) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL8122955 | 0.75 | OPRD1 (0.65) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL3667966 | 0.75 | L3MBTL1 (0.57) | LMNAGAASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9257372 | 0.75 | OPRM1 (0.54) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL23033301 | 0.73 | CHRM2 (0.40) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL9251268 | 0.73 | OPRM1 (0.59) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710661-B1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5716958-A | GASTROINTESTINAL DISORDERS; INHIBITORY ACTIVITY ON CHOLECYSTOKININ | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0710661-A1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |