Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 7/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913727 | 0.87 | KDM4E (0.37) | ALDH1A1KDM4EPOLBADRA1ASMN1; SMN2 | |
| SCHEMBL7910233 | 0.80 | CYP3A4 (0.34) | ALDH1A1HPGDHRH3 | |
| SCHEMBL7908118 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EALOX15 | |
| SCHEMBL7909786 | 0.77 | NAMPT (0.41) | ALDH1A1KDM4EALOX15HSD17B10HRH3 | |
| SCHEMBL7908933 | 0.77 | TSHR (0.41) | ALDH1A1ALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL7906027 | 0.76 | ACACB (0.32) | — | |
| SCHEMBL7909124 | 0.76 | BDKRB1 (0.34) | ALDH1A1FASNMGLL | |
| SCHEMBL13092177 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EPOLBALOX15 | |
| SCHEMBL7914100 | 0.75 | HRH3 (0.43) | HRH3 | |
| SCHEMBL7910389 | 0.73 | HRH3 (0.36) | ALDH1A1HPGDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010106081-A1 | PIPERIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-23 | — | — | WO | disclosed |