Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 12/20 | 0.41 |
| ▸ | PLAU | P00749 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
| ▸ | KLK1 | P06870 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502799 | 0.86 | HTR5A (0.56) | HTR5ASLC9A1 | |
| SCHEMBL7919941 | 0.84 | PLAU (0.41) | HTR5APLAUF2PLGPLAT | |
| SCHEMBL7916046 | 0.84 | HTR5A (0.39) | HTR5APLAUF2PLGPLAT | |
| SCHEMBL16502630 | 0.78 | PLA2G2D (0.46) | PLAUHCRTR1HCRTR2 | |
| SCHEMBL7916601 | 0.76 | TNF (0.43) | HTR5APLAUF2PLGPLAT | |
| SCHEMBL7918769 | 0.75 | CNR2 (0.39) | PLAUF2PLGPLATKLK1 | |
| SCHEMBL7916829 | 0.74 | ALOX15 (0.52) | HCRTR1HCRTR2NPC1 | |
| SCHEMBL7923157 | 0.73 | HTR5A (0.53) | HTR5ASLC9A1 | |
| SCHEMBL16502816 | 0.73 | HTR5A (0.51) | HTR5ASLC9A1 | |
| SCHEMBL16509478 | 0.73 | HTR5A (0.46) | HTR5ASLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |