Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2871462 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KDM4ETP53NPC1RAB9A | |
| SCHEMBL7914416 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4ETP53NPC1RAB9A | |
| SCHEMBL7913463 | 0.81 | ALDH1A1 (0.37) | ALDH1A1KDM4ETP53NPC1RAB9A | |
| SCHEMBL7914406 | 0.81 | CYP1A2 (0.38) | ALDH1A1KDM4ETP53NPC1RAB9A | |
| SCHEMBL7916401 | 0.81 | ADORA2A (0.43) | ALDH1A1KDM4ETP53NPC1RAB9A | |
| SCHEMBL7916445 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4ETP53MAPTTOP2A | |
| SCHEMBL7906142 | 0.78 | KDM4E (0.42) | ALDH1A1KDM4ERAB9AMAPTPDE10A | |
| SCHEMBL20975373 | 0.77 | KDM4E (0.46) | ALDH1A1KDM4ETP53NPC1RAB9A | |
| SCHEMBL12495116 | 0.72 | HTR2C (0.39) | ALDH1A1KDM4ETP53NPC1RAB9A | |
| SCHEMBL7913445 | 0.72 | KDM4E (0.41) | ALDH1A1KDM4ETP53MAPTTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297258-B1 | USEFUL AS ANTINEOPLASTIC AGENTS AND IN THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE. | AMERICAN CYANAMID COMPANY | 2001-10-02 | — | — | US | disclosed |