Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267187 | 0.93 | THRB (0.33) | THRB | |
| Potassium Ion SCHEMBL8031205 | 0.93 | CA4 (0.35) | THRB | |
| SCHEMBL2362326 | 0.93 | THRB (0.33) | THRB | |
| Lithium Ion SCHEMBL10456250 | 0.93 | THRB (0.33) | THRB | |
| SCHEMBL2517281 | 0.93 | THRB (0.33) | THRB | |
| SCHEMBL11537912 | 0.93 | THRB (0.33) | THRB | |
| Zinc Ion SCHEMBL10663858 | 0.93 | THRB (0.33) | THRB | |
| SCHEMBL2362883 | 0.93 | THRB (0.33) | THRB | |
| SCHEMBL5275789 | 0.93 | CA4 (0.35) | THRB | |
| Silver SCHEMBL11537905 | 0.93 | THRB (0.33) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10233541-B2 | Deposition of films containing alkaline earth metals | APPLIED MATERIALS, INC. (US) | 2019-03-19 | — | — | US | claimed |
| CN-104350175-A | Deposition of films containing alkaline earth metals | APPLIED MATERIALS INC | 2015-02-11 | — | — | CN | disclosed |
| US-6211096-B1 | Tunable dielectric constant oxide and method of manufacture | LSI LOGIC CORPORATION | 2001-04-03 | — | — | US | disclosed |