Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 3/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.56 |
| ▸ | LAP3 | P28838 | 2/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.55 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.55 |
| ▸ | METAP2 | P50579 | 2/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924570 | 0.92 | METAP2 (0.60) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 | |
| SCHEMBL7361190 | 0.82 | LAP3 (0.67) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 | |
| SCHEMBL7358146 | 0.81 | LAP3 (0.53) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 | |
| SCHEMBL7352471 | 0.81 | LAP3 (0.53) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL7353077 | 0.81 | LAP3 (0.66) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL7360809 | 0.80 | LAP3 (0.52) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 | |
| SCHEMBL7374328 | 0.80 | CYP2D6 (0.63) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 | |
| SCHEMBL29722572 | 0.80 | CYP2D6 (0.67) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 | |
| SCHEMBL7925096 | 0.80 | KMT2A (0.52) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL7499541 | 0.78 | METAP2 (0.61) | CYP2D6CYP2C9CYP2C19KMT2AMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235929-B1 | SELECTIVELY INHIBITING SERINE PROTEASES, SELECTIVELY INHIBITING CYSTEINE PROTEASES, | GEORGIA TECH RESEARCH CORPORATION | 2001-05-22 | — | — | US | disclosed |
| US-5763576-A | Tetrapeptide α-ketoamides | GEORGIA TECH RESEARCH CORP. (US) | 1998-06-09 | — | — | US | disclosed |