Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.60 |
| ▸ | LAP3 | P28838 | 2/20 | 0.58 |
| ▸ | ANPEP | P15144 | 1/20 | 0.58 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.58 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.58 |
| ▸ | METAP1 | P53582 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916657 | 0.92 | CYP2D6 (0.57) | METAP2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL7950693 | 0.85 | LAP3 (0.72) | METAP2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL14973840 | 0.84 | POLB (0.61) | METAP2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL9192833 | 0.83 | POLB (0.61) | POLBCA12CA2CA9MMP8 | |
| SCHEMBL10635162 | 0.83 | POLB (0.61) | POLBCA12CA2CA9MMP8 | |
| SCHEMBL9188615 | 0.79 | POLB (0.54) | METAP2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL7925124 | 0.79 | ADAM17 (0.46) | METAP2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL28028170 | 0.78 | METAP2 (0.66) | METAP2LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL28028169 | 0.78 | METAP2 (0.66) | METAP2LAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL4736960 | 0.78 | METAP2 (0.50) | METAP2LAP3ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235929-B1 | SELECTIVELY INHIBITING SERINE PROTEASES, SELECTIVELY INHIBITING CYSTEINE PROTEASES, | GEORGIA TECH RESEARCH CORPORATION | 2001-05-22 | — | — | US | disclosed |
| US-5763576-A | Tetrapeptide α-ketoamides | GEORGIA TECH RESEARCH CORP. (US) | 1998-06-09 | — | — | US | disclosed |