Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8859293 | 0.88 | MAOB (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11563826 | 0.88 | MAOB (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL291980 | 0.83 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31253538 | 0.82 | HDAC2 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL25321818 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL368442 | 0.79 | ALDH1A1 (0.78) | ALDH1A1TSHRMEN1KMT2AMAOB | |
| SCHEMBL16499669 | 0.79 | ALDH1A1 (0.78) | ALDH1A1TSHRMEN1KMT2AMAOB | |
| SCHEMBL15524520 | 0.78 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28670026 | 0.78 | NFE2L2 (0.59) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5139848 | 0.78 | MMP1 (0.54) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6217984-B1 | MONOMERIC ORGANOMETALLIC COMPLEX FREE OF NUCLEOPHILIC GROUPS, WHICH UPON EXPOSURE TO ENERGY, BONDS TO BASIC REACTIVE SITES ON A SUBSTRATE VIA METAL CENTER, LEAVING POLYMERIZABLE GROUP OF COMPLEX UNREACTED AND UNRESTRICTED | 3M INNOVATIVE PROPERTIES COMPANY | 2001-04-17 | — | — | US | disclosed |
| US-6132860-A | COUPLING POLYMER ADHESIVE TO ABRASIVE PARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-10-17 | — | — | US | disclosed |