Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916819 | 0.82 | ACHE (0.38) | KDM4EACHECACNB4CACNA1ACACNA1G | |
| SCHEMBL7911213 | 0.81 | CACNB4 (0.37) | KDM4EACHENPSR1CACNB4CACNA1A | |
| SCHEMBL927184 | 0.70 | SLC9A1 (0.61) | KDM4EACHESMN1; SMN2NPC1MAPK1 | |
| SCHEMBL7916794 | 0.70 | SLC9A1 (0.61) | KDM4EACHESMN1; SMN2NPC1MAPK1 | |
| SCHEMBL7912931 | 0.68 | SLC9A1 (0.59) | KDM4EACHESMN1; SMN2NPC1MAPK1 | |
| SCHEMBL7910322 | 0.68 | SLC9A1 (0.43) | KDM4EACHESMN1; SMN2NPC1MAPK1 | |
| Maleic Acid SCHEMBL7916788 | 0.65 | SLC9A1 (0.54) | KDM4EACHESMN1; SMN2NPC1MAPK1 | |
| SCHEMBL7911358 | 0.65 | SLC9A1 (0.38) | KDM4EACHESMN1; SMN2MAPK1RAB9A | |
| SCHEMBL3987674 | 0.65 | KDM4E (0.49) | KDM4EACHESMN1; SMN2NPC1MAPK1 | |
| SCHEMBL3988319 | 0.65 | KDM4E (0.49) | KDM4EACHESMN1; SMN2NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |