Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 5/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203689 | 0.89 | HTR1A (0.35) | LMNAMTNR1AMTNR1BADRA2ANOTUM | |
| SCHEMBL7913031 | 0.86 | ABHD6 (0.37) | MTNR1AMTNR1BADRA2A | |
| SCHEMBL7932404 | 0.86 | ABHD6 (0.37) | MTNR1AMTNR1BADRA2A | |
| SCHEMBL7921822 | 0.86 | ABHD6 (0.37) | MTNR1AMTNR1BADRA2A | |
| Hydrochloric Acid SCHEMBL10914162 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BADRA2ACA1CA2 | |
| SCHEMBL7924279 | 0.85 | MTNR1A (0.32) | MTNR1AMTNR1BADRA2AL3MBTL1CA1 | |
| SCHEMBL4599719 | 0.84 | CXCR5 (0.36) | RXRALMNANOTUMCXCR5KDM4E | |
| SCHEMBL12203624 | 0.81 | TACR1 (0.39) | ATM | |
| SCHEMBL29156256 | 0.81 | TACR1 (0.39) | ATM | |
| SCHEMBL7917604 | 0.80 | ADRA2A (0.47) | MTNR1AMTNR1BADRA2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |