Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11722438 | 0.79 | IDO1 (0.56) | MAPTSMN1; SMN2HTTKDM4EGAA | |
| SCHEMBL7836753 | 0.79 | HSP90AB1 (0.39) | MAPTSMN1; SMN2HTTKDM4EGAA | |
| SCHEMBL1149063 | 0.77 | MAPT (0.49) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL28114141 | 0.76 | PNMT (0.45) | MAPTSMN1; SMN2HTTKDM4EGAA | |
| SCHEMBL7919710 | 0.72 | TAAR1 (0.36) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7843 | 0.70 | — | — | |
| SCHEMBL8684287 | 0.69 | MEN1 (0.62) | MAPTSMN1; SMN2HTTKDM4EGAA | |
| SCHEMBL8684282 | 0.69 | IDO1 (0.48) | MAPTSMN1; SMN2HTTKDM4EGAA | |
| SCHEMBL6282006 | 0.69 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2HTTKDM4EGAA | |
| SCHEMBL22080375 | 0.69 | MEN1 (0.46) | MAPTSMN1; SMN2HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |