Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836753 | 0.89 | HSP90AB1 (0.39) | TAAR1ALDH1A1HSP90AB1KMT2ACYP3A4 | |
| SCHEMBL7919214 | 0.75 | KDM1A (0.42) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3985532 | 0.73 | HSP90AB1 (0.43) | TAAR1ALDH1A1PTGS1PTGS2HSP90AB1 | |
| SCHEMBL7917042 | 0.72 | MAPT (0.45) | ALDH1A1PTGS2HSP90AB1KMT2AMEN1 | |
| SCHEMBL28293837 | 0.71 | NPC1 (0.48) | ALDH1A1KMT2AMEN1SMN1; SMN2CNR1 | |
| SCHEMBL7806594 | 0.69 | MAOB (0.44) | TAAR1ALDH1A1PTGS1PTGS2HSP90AB1 | |
| SCHEMBL3989555 | 0.69 | KMT2A (0.49) | TAAR1PTGS1PTGS2KMT2ACYP3A4 | |
| SCHEMBL7919229 | 0.69 | PNLIP (0.40) | ALDH1A1KMT2ACYP3A4MEN1SMN1; SMN2 | |
| SCHEMBL9185748 | 0.69 | KMT2A (0.43) | TAAR1PTGS1PTGS2HSP90AB1KMT2A | |
| SCHEMBL7829968 | 0.69 | HSP90AB1 (0.46) | TAAR1ALDH1A1HSP90AB1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |