Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917739 | 0.78 | MEN1 (0.39) | ADRB2S1PR3ALDH1A1LMNAGAA | |
| SCHEMBL7922556 | 0.73 | TSHR (0.41) | ADRB2ALDH1A1MDM2KDM4ELMNA | |
| SCHEMBL7843623 | 0.69 | MEN1 (0.45) | ADRB2ALDH1A1LMNAGAAMAPT | |
| SCHEMBL7922537 | 0.69 | MAPT (0.39) | ALDH1A1KDM4ELMNAMAPTIDO1 | |
| SCHEMBL7919720 | 0.69 | L3MBTL1 (0.44) | FFAR2KDM4EMAPT | |
| SCHEMBL7919229 | 0.68 | PNLIP (0.40) | ALDH1A1KDM4EMAPTCYP3A4 | |
| Hydrochloric Acid SCHEMBL28619070 | 0.68 | MEN1 (0.44) | ALDH1A1LMNAGAAMAPTIDO1 | |
| SCHEMBL7919710 | 0.68 | TAAR1 (0.36) | ALDH1A1MAPTCYP3A4 | |
| SCHEMBL7910275 | 0.67 | MAPT (0.42) | ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL17816190 | 0.65 | TSHR (0.50) | ADRB2KDM4ELMNAMAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |