Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.77 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917111 | 0.81 | MAOB (0.62) | MAOBMRGPRX4APPABCB1 | |
| SCHEMBL5987976 | 0.81 | MAOB (0.76) | MAOBMRGPRX4APPABCB1MAOA | |
| SCHEMBL91264 | 0.81 | MAOB (0.67) | MAOBMRGPRX4APPABCB1 | |
| SCHEMBL791323 | 0.81 | MAOB (1.00) | MAOBMRGPRX4APPMAOANR4A2 | |
| SCHEMBL13332739 | 0.80 | MAOB (0.70) | MAOBMRGPRX4APPABCB1 | |
| SCHEMBL4638649 | 0.80 | MAOB (0.65) | MAOBMRGPRX4APPABCB1 | |
| SCHEMBL16710557 | 0.80 | MAOB (0.77) | MAOBMRGPRX4MAOANR4A2 | |
| SCHEMBL23720 | 0.80 | MAOB (0.60) | MAOBMRGPRX4APPABCB1 | |
| SCHEMBL7917245 | 0.80 | MAOB (0.77) | MAOBMRGPRX4APPABCB1MAOA | |
| SCHEMBL23719 | 0.80 | ENPP2 (0.65) | MAOBMRGPRX4APPABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |