Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 3/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502684 | 0.86 | PLAU (0.50) | F2BCHEKDM4ENPC1RAB9A | |
| SCHEMBL7919941 | 0.82 | PLAU (0.41) | F2BCHEKDM4ENPC1RAB9A | |
| SCHEMBL16503471 | 0.81 | DOT1L (0.39) | F2KDM4EMAPTL3MBTL1PLAU | |
| SCHEMBL7913890 | 0.81 | KDM4E (0.38) | F2KDM4EMAPTKMT2APLAU | |
| SCHEMBL16502716 | 0.79 | ALDH1A1 (0.48) | F2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL7918689 | 0.79 | KDM4E (0.45) | F2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL29986041 | 0.78 | BCHE (0.58) | BCHEKDM4ENPC1RAB9AMAPT | |
| SCHEMBL158912 | 0.78 | BCHE (0.58) | BCHEKDM4ENPC1RAB9AMAPT | |
| SCHEMBL13063585 | 0.78 | NPC1 (0.45) | BCHEKDM4ENPC1RAB9AMAPT | |
| SCHEMBL12588350 | 0.78 | NPC1 (0.40) | BCHEKDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |