Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918436 | 0.91 | ALOX5 (0.46) | ALOX5ALDH1A1TDP1MAPK1KMT2A | |
| SCHEMBL7918443 | 0.91 | ALOX5 (0.46) | ALOX5ALDH1A1TDP1MAPK1KMT2A | |
| Oxalic Acid SCHEMBL7917823 | 0.89 | ALOX5 (0.44) | ALOX5ALDH1A1TDP1MAPK1KMT2A | |
| Oxalic Acid SCHEMBL7917829 | 0.89 | ALOX5 (0.44) | ALOX5ALDH1A1TDP1MAPK1KMT2A | |
| SCHEMBL25377167 | 0.86 | TP53 (0.45) | ALDH1A1TDP1MAPK1TAS2R14LMNA | |
| SCHEMBL25377161 | 0.86 | TP53 (0.45) | ALDH1A1TDP1MAPK1TAS2R14LMNA | |
| SCHEMBL12283364 | 0.81 | TAS2R14 (0.54) | ALDH1A1MAPK1KMT2ATAS2R14LMNA | |
| SCHEMBL1934331 | 0.81 | TAS2R14 (0.54) | ALDH1A1MAPK1KMT2ATAS2R14LMNA | |
| SCHEMBL25373818 | 0.80 | YTHDC1 (0.44) | ALDH1A1LMNAL3MBTL1SMN1; SMN2TP53 | |
| SCHEMBL25373812 | 0.80 | YTHDC1 (0.44) | ALDH1A1LMNAL3MBTL1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211219-B1 | DRUGS, ANALGESICS AND AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 2001-04-03 | — | — | US | disclosed |