Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12229339 | 0.81 | ABHD6 (0.32) | CARM1PRMT6PRMT1ABHD6BACE1 | |
| SCHEMBL14123611 | 0.75 | ABHD6 (0.34) | CARM1PRMT6PRMT1ABHD6 | |
| SCHEMBL15545247 | 0.75 | CES1 (0.41) | CARM1PRMT6PRMT1ABHD6 | |
| SCHEMBL30421685 | 0.75 | CES1 (0.41) | CARM1PRMT6PRMT1ABHD6 | |
| SCHEMBL7918142 | 0.73 | BACE1 (0.33) | BACE1 | |
| SCHEMBL30842183 | 0.70 | SIGMAR1 (0.35) | CARM1PRMT6PRMT1ABHD6 | |
| SCHEMBL12789684 | 0.69 | ADRA2A (0.32) | CARM1PRMT6PRMT1ABHD6 | |
| SCHEMBL21936820 | 0.68 | ABHD6 (0.33) | CARM1PRMT6PRMT1ABHD6 | |
| SCHEMBL19045926 | 0.68 | ADRA2A (0.37) | ALDH1A1MAPT | |
| SCHEMBL30842146 | 0.67 | SIGMAR1 (0.33) | CARM1PRMT6PRMT1KDM4EABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |